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ANHUI BBCA PHARMACEUTICAL CO.,LTD
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P-aminophenol

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P-aminophenol API

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pharmaceutical grade P-aminophenol

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P-aminophenol active ingredient

Description
P-aminophenol
I. Chemical Structure
The p-aminophenol molecule contains a benzene ring, with an amino group and a hydroxyl group at the para position. This structure gives it special chemical properties. The amino group can react with acids to form salts, like reacting with hydrochloric acid to make p-aminophenol hydrochloride. The hydroxyl group is prone to electrophilic substitution, such as the esterification with acetic anhydride to form paracetamol, crucial in pharmaceutical synthesis.
II. Physical and Chemical Properties
  1. Appearance: Usually, it's a white or light yellow crystalline powder. In air or poor storage, it darkens due to oxidation.
  1. Solubility: Slightly soluble in water because of the benzene ring's hydrophobicity. But it dissolves well in ethanol, ether, and alkaline solutions. In ethanol, hydrogen bonds help its dissolution.
  1. Stability: The amino group's strong reducibility makes p-aminophenol unstable in air. It oxidizes from the amino group, changing color from white/light yellow to brown or black, affecting its properties. To keep it stable, store it sealed, controlling temperature and humidity.
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