|Place Of Origin:||China (Mainland)||Brand Name:||BBCA|
|Other Names:||Pharmaceutical Tablets 25mg Naftopidil Tablets||Grade:||Medicine Grade|
1. Product Name: Pharmaceutical Tablets 25mg Naftopidil Tablets
2. Component: This article main ingredients for naphthalene in, its chemical name is: (+) - 1 - [4 - (2 - phenyl methyl oxygen) - piperazine base] - 3 - (1 -) naphthalene oxygen radicals - 2 - propanol.
3. Appearance: This product is a white sheet.
4. Indications: Urination disorder caused by benign prostatic hyperplasia.
5. Specifications: 25mg
6. Usage and Dosage: Oral.Adults usually initial dosage for a 25 mg (1), 1 times a day, to take before going to bed dose appropriate adjustments can be made with the clinical curative effect, maximum daily dose should not exceed 75 mg (3 pieces), elderly patients should be low dose (12.5 mg/day), at the same time pay attention to supervision.
7. Contraindications: Allergy to this product are prohibited.
8. Pharmacological mechanisms: Healthy adults respectively single oral this product on an empty stomach after 25 mg, 50 mg and 100 mg, Tmax were 0.45 + / - 0.21, 0.75 + / - 0.71 and 0.71 + / - 0.22 hours, Cmax were 39.3 + / - 10.3, 70.1 + / - 32.9 and 32.9 + / - 55.8 mg/ml, half-life were 15.2 + / - 4.7, 10.3 + / - 4.1 and 4.1 + / - 13.7 hours.After taking this product a 50 mg, twice a day, just 4 times after the blood drug concentration reached steady state.Healthy adult single take 25 mg, 50 mg, 100 mg of this product, after 24 hours urine prototype drug excretion rate less than 0.01%.The main metabolites of glucuronic acid combination and methoxyl phenyl hydroxide.Healthy adult fasting and postprandial single take 50 mg, Tmax 0.75 hours and 2.20 hours respectively, postprandial serum drug concentration time slightly increased area under the curve, the peak concentration and no change was found in all phase elimination half-life, prompt food less influence the absorption of this product.Healthy adults hollow when single oral 100 mg, serum protein combined rate of 98.5%.
9. Storage: Airtight preservation.
10. Package: 10pcs/blister;10blisters/box; 100Boxes/Carton