1. Product Name: Powder for Injection Made in China Heparin Sodium Injection
2. Component: This article main ingredients for heparin sodium.
3. Appearance: This product is colorless to light yellow transparent liquid.
4. Indications: Used for the prevention and treatment of thrombosis or embolism disease (such as myocardial infarction, thrombophlebitis, pulmonary embolism, etc.);Various causes of diffuse intravascular coagulation (DIC);Also used in hemodialysis, extracorporeal circulation, catheter, such as microvascular surgery operation and some blood specimens or instrument of anticoagulant treatment.
5. Specifications: 2ml: 5000U
6. Usage and Dosage:
1). Deep subcutaneous injection: 5000 ~ 10000 units, for the first time after every 8 hours of 8000 ~ 10000 unit or every 12 hours and 15000 ~ 15000;Every 24 hours total about 30000 to 40000 units, general can achieve satisfactory results.
2). Intravenous: 5000 ~ 10000 units for the first time, or by 100 units/kg body weight every 4 hours, with sodium chloride injection diluted applications.
3). The intravenous drip: 20000 ~ 40000 units per day, plus continuous drip to 1000 ml of sodium chloride injection.But before drip as initial dose intravenous 5000 units.
4). Preventive treatment: high-risk patients with thrombosis, is mostly used for after abdominal surgery, to prevent deep venous thrombosis.In 2 hours before surgery to 5000 units of heparin subcutaneous injection, but the type of anesthesia should avoid epidural anesthesia, then every 8 ~ 12 hours 5000 units, a total of about 7 days.
Allergic to heparin, have spontaneous bleeding tendency, slow blood clotting (such as hemophilia, purpura, thrombocytopenia), ulcer disease, trauma, postpartum hemorrhage and severe hepatic insufficiency were banned.
8. Pharmacological mechanisms:
This product oral absorption, subcutaneous, intramuscular, or static note well absorbed.But 80% heparin combined with plasma albumin, is blood adsorption, some gaps can diffuse to the outside of the vascular tissue.Because of its high molecular weight, not by the pleura.Peritoneal and placental tissue.This article mainly in the reticuloendothelial system metabolism, kidney excretion.With a small amount of prototype to discharge.Static note after the discharge depends on to the dose.When one gives 100, 400 or 800 u.T1/2 for 1 hour, 2.5 hours and 5 hours.Chronic kidney dysfunction and excessive obesity, metabolic discharge delay, may accumulate;This product work time related to drug delivery methods, static note immediate best anticoagulant effect, but the individual difference is bigger, subcutaneous injection for absorption of individual differences, so the overall duration extended obviously.Within the plasma heparin concentration is not affected by dialysis.
9. Storage: Shading, airtight, preserved in the shade (not more than 20 ℃).
10. Package: 10 Vials/Box; 50 Boxes/Carton
|Doasge:||Injection||Color:||Colorless To Light Yellow|